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What to monitor Visible changes: Skin texture and tone Fine line depth Hair density and quality Wound healing speed Subjective factors: Energy levels Sleep quality General sense of wellbeing Side effects: Injection site reactions Skin flushing Fatigue (especially early in use) Photograph yourself in consistent lighting at baseline and every 4 weeks

Serious side effects are rare in small studies, but risks include: Injectionsite infection or allergic reaction

Levodopa and cobalamin-related neurotoxic metabolites and benefits of COMT inhibitors The breakdown of LDopa through COMT requires methyl group transfer, leading to the formation of the stable compound 3-O-MethylDopa (Mller and Riederer 2023)

This does not mean they are illegal to possess

This means that with each subsequent puncture, you're increasing the risk of introducing bacteria that can now freely multiply within the solution